| Term: | nervous system phosphatidylinositol 3-kinase/protein kinase B signal transduction |
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| Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
| Name: | nervous system |
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| Synonyms: | |
| Definition: | A regulatory system of the body that consists of neurons and neuroglial cells. The nervous system is divided into two parts, the central nervous system (CNS) and the peripheral nervous system (PNS). |
| Ontology: | Anatomy Ontology [ZFA:0000396] |
| Name: | phosphatidylinositol 3-kinase/protein kinase B signal transduction |
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| Synonyms: | AKT signal transduction, AKT signaling, AKT signaling cascade, AKT signalling cascade, phosphatidylinositol 3-kinase signaling/protein kinase B signal transduction, PI3K-PKB/Akt pathway, PI3K/Akt signal transduction, PI3K/PKB signal transduction, PKB signal transduction, PKB signaling, PKB signaling cascade, PKB signalling cascade, protein kinase B signal transduction, protein kinase B signaling, protein kinase B signaling cascade, protein kinase B signalling cascade |
| Definition: | An intracellular signaling cassette that starts with phosphatidylinositol 3-kinase (PI3K) activation, production of phosphatidylinositol 3-phosphate (PI3P), activation of PDK1, which recruits and ending with the activation of protein kinase B (PKB, also known as Akt). PI3K is activated by cell surface receptors. Note that PTEN is an inhibitor of the pathway. |
| Ontology: | GO: Biological Process [GO:0043491] QuickGO AmiGO |